Women’s health knowledge translation initiative & science communication training program

Co-lead:

  • Katherine Moore
    UBC

Team members: 

  • Sarah Munro
    CHÉOS
  • Lori Brotto
    Women’s Health Research Institute
  • Marina Adshade
    UBC
  • Shirley Weir
    Menopause Chicks
  • Patricia Tomasi
    Canadian Perinatal Mental Health Collaborative
  • Melissa Nelson
    Women’s Health Research Institute
  • Bonnie Vockeroth
    UBC
  • Victoria Gay
    BC Women’s Foundation
  • Vanessa Hrvatin
    Centre for Brain Health
  • Bonnie Lee
    UBC
  • Lesa Dawson
    Memorial University
  • Beverley Pomeroy
    BC Support Unit

The proposed project will provide opportunities for multidisciplinary trainees to develop and strengthen their science communication skills by learning from experts and gaining hands on experience translating knowledge using multiple mediums—a women’s health podcast, video series and blog. These KT products will draw attention and dispense knowledge to the public and the scientific community about women’s health research. Why is this important to convey? Although funding agencies mandate the inclusion of both sexes, women’s health is much more than how they differ from men. Women’s health is directly influenced by physiological and  societal challenges that are unique to women. There is a critical need to convey how different physiological experiences (menstruation, pregnancy, menopause) influence women’s health and how gendered experiences and expectations drive disparities in women’s health (e.g. greater misdiagnosis in women compared to men). For example, oral contraceptives influence depression risk depending on a woman’s age or whether she is pregnant, postpartum or menopausal, as these factors differentially influence drug efficacy. MSFHR funding will provide payments for research users and trainees to produce outputs.

Reimagining perinatal mental health services: Collaborative development of an integrated model of care

Co-lead: 

  • Michelle Carter
    Providence Health Care

Team members: 

  • Wendy Hall 
    UBC
  • Angela Russolillo
    St. Paul's Hospital
  • Brittany Bingham
    VCH Aboriginal Health
  • Christine Ou
    UBC
  • Valerie Rychel
    St. Paul's Hospital
  • Sheila Duffy
    Pacific Post Partum Society
  • Nichole Fairbrother
    UBC

Perinatal mood and anxiety disorders (PMADs) are the most common obstetrical complication in Canada, with serious implications for both the mother and infant. Untreated PMADs are associated with increased risks for poor health and social outcomes, including maternal suicide and medical complications as well as impaired infant and child development. There is increasing scientific evidence that collaboration across clinical services is essential to addressing the complex biopsychosocial needs associated with PMADs. Nevertheless, perinatal mental health (PMH) services in Canada remain fragmented, often resulting in missed opportunities to support necessary care and treatment. 

There is an immediate need to improve the access and integration of services for PMADs in BC. In an effort to narrow the evidence to practice gap, we plan to create a collaboration between clinicians, researchers and individuals with lived experience through a scientific consensus process (Delphi approach) and one-day virtual workshop. Our main objective is to develop an evidence-based, user-informed model of care to advance integrated PMH care delivery in BC and beyond.

A collaborative project to explore COVID-19 rapid redesign and redeployment best practices and their uptake in British Columbia long-term care sector

Co-lead: 

  • David Keselman
    Louis Brier Home and Hospital

Team members:

  • Karen Neilson
    BC Ministry of Health
  • Heather Cook 
    BC Ministry of Health
  • Maura McPhee
    UBC
  • Alison Phinney
    UBC 
  • Sabina Staempfli
    UBC
  • Jennifer Stokes
    Island Health
  • Ayako Nilssen
    Island Health
  • Vicki Andersen
    Louise Brier Home and Hospital
  • Mirsad Dragic
    Louis Brier Home and Hospital
  • Keren Gersman
    Louise Brier Home and Hospital
  • Dan Galazka
    Louise Brier Home and Hospital
  • Michael Kary
    BC Care Providers Association
  • Pam Baxter 
    McMaster University

In Canada, 81% of COVID-19 deaths were in long-term care (LTC) settings. To slow the virus spread, the BC government mandated LTC sites to introduce a series of new practices and policies. For example, families and visitors were no longer allowed into LTC sites; and staff were banned from working in more than one location. In June 2020, our research team received an MSFHR grant to examine the intended and unintended consequences of these practices and policies on residents, families and staff in a ‘gold standard’ publicly funded facility with no COVID cases. We have had many interesting findings related to effective pandemic management to date, but it is unclear if these findings are applicable to other BC LTC sites.

The proposed project will bring together nearly 170 researchers and research users across 5 regional health authorities to identify best pandemic management practices and policies and to discuss strategies for their uptake. The network represents 7 key stakeholder groups including policy/advocacy, leadership and resident and family representatives. The project outcomes include recommendations for effective pandemic management in publicly funded BC LTC sites and a research advisory group to support future research.

Building a collaborative research agenda for virtual exercise and nutrition supportive cancer care in BC​

Co-lead: 

  • Alan Bates
    BC Cancer

Team members: 

  • Cheri Van Patten 
    BC Cancer
  • Stuart Peacock 
    SFU
  • Helen McTaggart-Cowan 
    SFU
  • Guy Faulkner
    UBC
  • Alina Gerrie
    BC Cancer
  • Nathalie LeVasseur
    BC Cancer
  • Rosemary Cashman
    BC Cancer
  • Kendra Zadravec
    UBC
  • G. Haukur Guomundsson
    UBC
  • Scott Lear
    SFU
  • Jeremy McAllister
    Physiotherapy Board of BC

The Nutrition and Exercise During Treatment (NEXT) Program is a long-standing collaboration (since 1999) between BCC and the UBC. In-person programming has been developed, research tested, and then offered to BCC patients. To meet evolving health needs, especially for British Columbians who live in rural and remote locations, coupled with the evolving needs for the current pandemic, we need to further develop tools to effectively shift into virtual models of care. This collaborative project will bring together a working group to plan and prioritize a research agenda to develop accessible and effective virtual (online) supportive care (exercise and nutrition programs) for people living with, and beyond, cancer in British Columbia. This collaboration will include a core working group of researchers (UBC, Simon Fraser and BCC), patient partners and people working in delivery and administration of clinical cancer care in British Columbia (Patient Partners, Allied Health Professionals, Oncologists, Nurse Practitioners, and Administrators).

Development and evaluation of a novel wearable gait analysis tool for remote monitoring and assessment of patients with musculoskeletal injuries

Regular physical activity is known to produce significant physical and mental health benefits, yet only 15% of Canadian adults meet the recommended guidelines. Running is one of the most popular leisure-time physical activities and is effective even in low doses. However, runners sustain a high rate of musculoskeletal injury, with up to 50% suffering an injury annually. Many injuries are due to abnormal running form. The emergence of wearable technology has presented an opportunity not only to collect information on running form outside of a research lab setting, but also remotely. This project aims to develop and evaluate an innovative remote gait assessment system using wearable technology that will allow clinicians to measure, monitor, and reassess patients with gait impairments remotely. This tool has the potential for physiotherapists to assess running injuries clinically in a way that currently is only possible in research settings. The development of a clinical assessment tool to objectively measure running gait outside of a lab is an exciting opportunity especially as COVID-19 is reshaping the way health care is delivered and increasing telehealth options for clinicians to work remotely.

Motor vehicle crash risk after cardioverter-defibrillator implantation: A population-based evaluation

Motor vehicle crashes result in 78 million injuries worldwide each year. Some crashes might be prevented by restricting driving for individuals with medical conditions that might cause sudden incapacitation while diving (eg. epilepsy, sleep apnea).

About 4,000 Canadians will have an implantable cardiac defibrillator (ICD) implanted this year. ICDs treat life-threatening cardiac rhythm abnormalities and prevent cardiac arrest. A heart rhythm problem or device malfunction in the weeks after implantation might result in a crash, so patients are warned not to drive for 4 weeks after ICD implantation.

Do driving restrictions after ICD implantation prevent crashes? Would driving restrictions be more effective if they were modified? The answers to these questions aren't known.

British Columbia's health and driving databases provide a unique opportunity to examine crash risk after ICD implantation. The MVC-ICD study will use health and driving records to compare crash risk among 9,000 ICD patients to crash risk among control patients. Results will provide an immediate opportunity to improve clinical practice, licensing policy and road safety in Canada and abroad.

Implementing quality indicators through clinician and patient online toolkits to improve rehabilitation care and outcomes after hip and knee replacement for osteoarthritis

Each year, more than 18,000 British Columbians have joint replacement surgery for hip or knee osteoarthritis. Many face challenges in getting timely, quality rehabilitation before, and especially after surgery. I have developed quality indicators that set minimum standards of rehabilitation care for joint replacements. Focusing on 10 of these quality indicators for care after surgery, my team of clinicians, patients and researchers have created online toolkits to help make these indicators available to patients and clinicians who provide joint replacement rehabilitation in BC. The toolkits contain resources such as checklists, videos, and posters. After first testing our study procedures, I will run a study to see if the toolkits make a difference in overall quality of rehabilitation care and lead to better experiences and results for patients. Patients, clinicians and those who make decisions about healthcare services, will be part of every stage of this work. I will share my findings widely to researchers, clinicians and patients locally and across Canada. This research will lead to better, more consistent care for patients and improve the joint replacement rehabilitation services available in BC.

3D printing of hydrogel tubing via reactive hydrodynamic focusing to replace single-use plastic medical tubing

Single-use plastic medical tubing is widely used in hospitals. Although practical, plastic tubing has a potentially life-threatening problem in that blood cells and proteins can deposit on the tubing to form clots. There are also problems with being unable to dispose of the plastic tubing in an environmentally-friendly manner. Commercially available plastic tubing has seen little change over the last 30 years.

We propose replacing plastic tubing with a 3D printed tube made from compostable materials. Our tubes are based on a substance called a hydrogel, have excellent mechanical and fluid movement properties, and are bio-compatible (do not cause reactions in people). Our approach is technically and economically feasible for scale-up. We target MSFHR health priority #3. We will provide on-demand printing of hydrogel tubing, replacing existing plastic tubing used, e.g. dialysis, to allow clinicians to rapidly customize tubing shape, size, and composition to adapt specific treatment needs. At the end of its life-cycle, our tubing is compostable, which will reduce single-use plastic and open up new pathways for environmentally-friendly disposal.

Critical Illness Survivorship: Evidence to Design Patient-Centred Interventions

Over 80% of patients who are treated in the intensive care unit (ICU) for a life-threatening illness face reduced physical health, emotional wellbeing and quality of life. Up to half of patients discharged from the ICU are readmitted to hospital within a year with complex medical conditions. This is a tremendous cost of cure for survivors and their family caregivers. Services for patients with complex medical conditions and/or frail patients is a BC Health System Priority.

This research aims to identify patient- and family-perspectives for designing healthcare services that meet their needs. The primary study will involve interviewing ICU patient survivors, their family members and healthcare providers to map the causes of hospital readmission.

These results will inform the design of services to reduce hospital readmissions. The results of these studies will be shared with national and international researchers and clinicians to benefit patients across Canada.

The Cedar Project: Preparing for Culturally-Safe, Trauma Informed COVID-19 Response Among Urban Indigenous People Who Use Drugs in BC

Indigenous people who use drugs in BC are facing two public health emergencies: COVID-19 and the ongoing overdose crisis. One likely creates additional risk for the other. On one hand, COVID-19 and its response may affect access to clean smoking/injection equipment, safe supply of illicit drugs, income, and health and social services. Pandemic fears and restrictions may also impact mental wellbeing. On the other hand, substance use may increase COVID-19 risk through sharing smoking/injection equipment; barriers to physical distancing; and housing instability. Our study assesses impact of COVID-19 and the pandemic response, as well as its domino effects, among Indigenous people who use drugs. The study will inform a culturally-safe, trauma informed response for this population.