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…Her-2 subtype. These tumours produce a protein called Her-2, which helps the cells grow uncontrollably. The drug Herceptin acts against the Her-2 protein. While this drug is effective, there are…
…are also SPOR SUPPORT Units located in Alberta, Manitoba, the Maritimes, Newfoundland and Labrador, the Northwest Territories, Ontario, Quebec, Saskatchewan, and Yukon. Discussions are underway to establish a SUPPORT Unit…
…addition of new neurons (neurogenesis) in the hippocampus is involved in or may even be required for the normal functions of this region. The rate of neurogenesis declines with age….
…daf-2, which is the worm version of the human insulin and insulin-like growth factor receptor. When this gene is mutated in worms (C. elegans), they live twice as long. Victor…
…immune response. Examples of diseases with hyperinflammatory phenotypes include, cystic fibrosis (CF) and inflammatory bowel disease (IBD). Matthew Mayer is studying the immune systems of children and adults with these…
…Institutes of Health Research’s (CIHR) Strategy for Patient-Oriented Research (SPOR) Networks in Chronic Disease, connecting researchers, health professionals, policy-makers, and patients across the country. MSFHR has committed funding over five…
…in cells that have increased metabolism (i.e., cancer cells). Unfortunately, [18F]-FDG is not cancer-specific and also tends to bind to other tissues such as brain and bladder, and at sites…
…quorum-sensing, and antibiotic synthesis. By using a combination of ancestral sequence reconstruction and experimental protein evolution, this project will explore how these proteins took up new regulatory roles, resulting in…
…deliver nutrients to survive and grow. In heart disease, blood vessels are blocked by hardening of the arteries. When not enough blood gets to the heart, tissue dies, causing a…
Synthetic DNA can potentially be used to develop new drugs that target infectious diseases and cancer. I am studying how to create new molecules based on DNA. My research team…