Schizophrenia and bipolar disease are severe mental illnesses that affect thinking, mood and behaviour, and cause lifelong disability. Schizophrenia alone costs the Canadian economy about $2.5 billion per year. While…
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…and found a protein, TMEM119, to be extremely specific to Osteosarcoma. We have demonstrated that TMEM119 is not expressed in normal tissues, only in some sarcomas, making it an ideal…
…again for every outbreak. Finally, I want to combine genomics and advanced data analysis (bioinformatics) to establish a method of integrating epidemiological, political, and other contextual information with genomic data…
…studying temporal processes, such as differentiation and development. How are cell types stabilized? How do they destabilize in diseases like cancer and with age? However, it is not currently possible…
…and neurodegenerative diseases such as schizophrenia, Alzheimer’s, Parkinson’s and Huntington’s disease. Cell adhesion molecules, localized at synapses, are believed to have an important role in the regulation of synapse formation,…
Contrary to popular belief, neurogenesis—the creation of new neurons—occurs in the adult brain in all species, including the human. Research demonstrates that hormones play a role in neurogenesis; however, research…
…BC Ministry of Mental Health & Addictions. The 11 Fellows are part of a national cohort of 51 individuals based in Ontario (28), BC (11), Quebec (7), Alberta (1), Saskatchewan…
…fundamental biological research, to the diagnoses of disease, and to the development of medical interventions. New technologies are needed to enable continuous monitoring of large numbers of single cells, subject…
By 2040, 25% of Canadians will have osteoarthritis (OA), a disabling joint disease. This number will be as high as 50% for those who hurt their knee playing youth sport….
…immune-modulating drugs in obese, diabetic mice, and measuring the anti-inflammatory and anti-diabetic effects. With close to half a billion people worldwide suffering from T2D, we believe that the proposed cell-specific…