…test the ability of exercise to reduce the energetic demands of walking. Under Pillar C, she will investigate the effects of financial incentives to increase adherence to physical activity among…
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…Perona-Wright will test her hypothesis using a number of contrasting infections and a set of transgenic mice that allow her to follow cytokine production and cytokine signaling as they happen,…
…effects of acute stress. Here, he will test the hypothesis that new neurons are recruited during stressful experiences, and form memories of stressful experiences. A specific role in responding to…
…patients who have screened positive for depression. Portions of Dr. Mackay’s work will be observational and some (in collaboration with other researchers) will test the clinical application of novel technologies,…
…will test the hypotheses that daily CTX use in HIV-infected children causes the population of the microbes in their intestines to show: An increase in the number of antibiotic resistance…
…ACP Mastoparan by substituting every amino acid in its chain with every other naturally occurring amino acid. A peptide array will be used to test which amino acids are vital…
…kind of antibodies (IgE) is associated with allergic asthma development in humans, and treating mice with antibiotics results in high levels of IgE. We will test whether changing IgE levels…
…at least half of foam cells in human plaques come from artery smooth muscle cells. Mouse models are routinely used to study and test new therapies for atherosclerosis, but little…
…with a single genome sequence test on the bacteria. It has also shown that comparing the mutations in the genomes of bacteria from different patients allowed us to reconstruct the…
…responses, such as cell growth, movement, or death. In this project, I will test whether Panx1 conduits promote cell death following neuronal swelling. I will also examine the mechanisms through…