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…is working to identify and validate biomarkers to monitor the severity of spinal cord injuries (SCI), and allow the “real time” ongoing evaluation of candidate drugs in human clinical trials….

Pharmaceutical Outcomes and Policy Innovation

…in asthma care and patient compliance with treatment; examining how to assess “real life” drug effectiveness in patients who may have multiple medical conditions, especially seniors; evaluating five provincial drug…

Structural dynamics of hERG potassium channel gating studied using voltage clamp fluorimetry

…a new fluorescence technique that he established as a post doctoral fellow that provides a real-time analysis of the protein motions that cause hERG channels to open and close. With…

Formation, stabilization, and dynamic modulation of GABAergic inhibitory synapses in the central nervous system

…specific needs of the neuron to fit into a fully-functioning brain. He is watching the growth and maturation of synapses over a period of several days, observing in real-time the…

New Perspectives on Gender, Diversity, and Health Policy, Planning, and Services

…into account in health planning, implementation and research can result in real economic and human costs for health care consumers. These include lost opportunities, ill health, suffering and perhaps overall,…

From Efficacy to Community Effectiveness. The proposed program of research, mentoring and knowledge translation will addresses the more effective, scalable, population-based, chronic disease and that …

…care providers, community partners or patients. Dr. Janusz Kaczorowski aims to generate more high quality research evidence by end-users themselves, and under clinical conditions that closely resemble real life primary…

New indications for old drugs: Do statins, angiotensin converting enzyme inhibitors or proton pump inhibitors impact long-term disease progression in multiple sclerosis?

…be beneficial in the treatment of MS. There is a shortage of clinical data supporting the beneficial effects of these drugs in MS treatment. This project will study the real-world…

Characterizing Arm Recovery in People with Severe Stroke (CARPSS)

…be performed for fifty adults with severe upper limb impairment after their first stroke. Their upper limb use during training and real world settings will also be documented. This research…

The cost effectiveness of personalized medicine: Using a biomarker-driven treatment strategy for Rheumatoid Arthritis

…be treated, saving money, and giving patients effective treatment earlier. What is not known is whether these tests can actually improve patient outcomes and save costs in real life. This…

Wealthy and healthy: Socioeconomic status (SES) and syndemics

…data linkages. Our goal is to shed light on whether real-time data linkage could improve delivery of health services to core groups of people living with HIV. Ultimately, this work…