Tillie-Louise Hackett

Dr. Tillie-Louise Hackett began her academic appointment at UBC as an assistant professor in 2013. Her research program is focused on understanding the disruption of normal repair processes within the epithelial-mesenchymal trophic unit (EMTU) of the lung and how this propagates inflammation and tissue remodeling in patients with obstructive lung disease.

Dr. Hackett’s laboratory uses an innovative and targeted approach to isolate cells from donor lungs guided by Computed Tomography imaging. This resource, The Human Lung Cell Repository, aims to provide highly characterized cells representative of a variety of lung disease states and healthy individuals for use in clinical bio-assays of disease.

The goal of this research program is to further understand the airway microenvironment to determine therapeutic targets to prevent the initiation and perpetuation of pathological processes which contribute to obstructive airway diseases like asthma and chronic obstructive pulmonary disease.


University: University of British Columbia
Faculty: Medicine
Department: Anesthesiology, Pharmacology & Therapeutics
Position: Assistant Professor
Research Location: St. Paul’s Hospital