Sruthi Purushothaman

My journey in the field of tissue regeneration began in 2011 at the Centre for Cellular and Molecular Biology, India using zebrafish and brittle star models. Subsequently I joined the tissue regeneration laboratory of Dr. Ashley W. Seifert at the University of Kentucky where I identified the role of key molecular players regulating limb development in the amphibian model axolotl, one of the only animal models that can completely restore an amputated limb. With a desire to specialize in mammalian tissue regeneration, for my postdoctoral training I joined the laboratory of Drs. Freda Miller and David Kaplan at the SickKids, Toronto. Presently I am a postdoctoral research fellow with Freda Miller at the Michael Smith Laboratories, U.B.C. My work focuses on multi-tissue regeneration in mice, using fingertip (digit tip) regeneration as a model system. My goal following my training is to establish an academic research program that uses both amphibian and mammalian models to answer fundamental research questions in limb regeneration and use this information to develop new clinical approaches to enhance tissue regeneration following traumatic and diabetes-associated injuries in humans.