Evica Rajcan-Separovic

Dr. Evica Rajcan-Separovic is an associate professor in the Faculty of Medicine at the University of British Columbia. She has a PhD in molecular cytogentics and received her clinical training at the Children’s Hospital of Eastern Ontario (Ottawa). She has also been a member of the Canadian College of Medical Genetics since 1998.

Rajcan-Separovic holds operating grants from the Canadian Institutes of Health Research, and is a co-PI on grants funded by the Canadian Foundation of Innovation and the US Department of Defense (DoD) office of the Congressionally Directed Medical Research Programs (CDMRP).

Current research interests include identification of genetic causes of human diseases using new technologies such as chromosome microarrays and next generation sequencing. She is particularly interested in finding the genetic etiology of human postnatal and prenatal developmental abnormalities (e.g. intellectual disability and developmental abnormalities of human embryos and fetuses, respectively) and studying their functional consequences at the cellular level.

Recent Publications

Ying Qiao, Christine Tyson, Monica Hrynchak, Elena Lopez-Rangel, Jeanette Hildebrand, Sally Martell, Celina Fawcett, Levina Kasmara, Kristina Calli, Chansonette Harvard, Xudong, Liu, Jeanette J.A. Holden, M. E. Suzanne Lewis, Evica Rajcan-Separovic. Clinical application of 2.7M Cytogenetics array for CNV detection in subjects with idiopathic autism and/or intellectual disability, Clinical Genetics, 2013 Feb;83(2):145-54

Rajcan-Separovic Evica : Chromosome microarrays in human reproduction. Human Reproduction Update. 2012 Sep;18(5):555-67.

Liu X, Malenfant P, Reesor C, Lee A, Hudson ML, Harvard C, Qiao Y, Persico AM, Cohen IL, Chudley AE, Forster-Gibson C, Rajcan-Separovic E, Lewis ME, Holden JJ. 2p15-p16.1 microdeletion syndrome: molecular characterization and association of the OTX1 and XPO1 genes with autism spectrum disorders. Eur J Hum Genet. 2012 Jul;42(7):1459-69.

Harvard C, Strong E, Mercier E, Colnaghi R, Alcantara D, Chow E, Martell S, Tyson C, Hrynchak M, McGillivray B, Hamilton S, Marles S, Mhanni A, Dawson AJ, Pavlidis P, Qiao Y, Holden JJ, Lewis SM, O’Driscoll M, Rajcan-Separovic E. Understanding the impact of 1q21.1 copy number variant. Orphanet J Rare Dis. 2011 Aug 8;6:54.

Qiao Y, Harvard C, Tyson C, Liu X, Fawcett C, Pavlidis P, Holden J, Lewis S, Rajcan-Separovic E (2010) Outcome of array CGH analysis for 255 subjects with intellectual disability (ID) and search for candidate genes using bioinformatics, Hum Genet. 2010, Aug;128(2):179-94.