Dr. Christopher Rider is currently a postdoctoral researcher in the Carlsten lab working on the effects of air pollution exposure on corticosteroid responsiveness and DNA methylation in asthma. He has published extensively on how corticosteroid-inducible gene expression reduces inflammation and is affected by pro-inflammatory stimuli.
He previously completed a PhD in respiratory sciences in Dr. Newton’s lab at the University of Calgary. His early work demonstrated that inflammatory stimuli, including cytokines and cigarette smoke, reduce the ability of corticosteroids to enhance the expression of anti-inflammatory genes in asthma. He also showed that human rhinovirus could also repress corticosteroid-inducible anti-inflammatory gene expression, a novel mechanism that may contribute to the clinically observed corticosteroid resistance often seen during respiratory infections. Dr. Rider has also assessed corticosteroid-inducible gene expression in samples obtained from the lungs of healthy volunteers after inhaling a corticosteroid. His research productivity has led to 20 publications, 616 citations and an h-index of 12.
For an up-to-date list of publications by Dr. Rider, please see Google Scholar.