Triggered release of anti-cancer drugs using hybrid lipid nanoparticle technology

Drugs used in cancer treatment, unfortunately, also can harm healthy cells. We’re working on a better way to deliver these drugs directly to cancer cells, minimizing damage to healthy tissues. Imagine tiny particles, like microscopic delivery trucks, that carry cancer drugs. These particles are made from fats and can hold both a cancer-fighting drug, doxorubicin, and special iron particles. What’s unique about these tiny trucks is that they release their drug only when hit by a certain type of radio wave. This means we can target the drug right at the cancer cells, releasing it quickly and precisely. Our first goal is to make these special particles. Then, we’ll test if we can use radio waves to release the drug quickly in lab experiments. Lastly, we hope to show that this method works well in treating cancer in animal studies. Previously, our team has successfully translated scientific research into practical therapies, and we believe this might be yet another example of our achievement in advancing the efficacy of cancer therapy and safety.