COVID-19 poses a significant threat to Urban Indigenous populations. To identify gaps and improve the response, Vancouver Coastal Health Aboriginal Health will use a community-driven approach to examine patient data collected within Vancouver health centres using the Vancouver Community Analytics Tool (VCAT), along with the advice of key urban Indigenous community organizations and stakeholders. Analyzed data will be used to develop an extensive data profile of Indigenous peoples who access care in the Vancouver region, including COVID-19 risk, comorbidities, and impacts to health service access. We will review the current Urban Indigenous COVID-19 response in Vancouver with existing networks to develop recommendations for BC that are driven by and for the Urban Indigenous community.