The Centre for Heart Lung Innovation (HLI) was established as the Pulmonary Research Laboratory in 1977 by Drs. James Hogg and Peter Pare. Since then, it has grown dramatically in scope, size and worldwide impact.
Basic and clinician scientists work together in an exciting multidisciplinary environment to address vital issues in heart, lung and critical care disease. Situated within Providence Health Care’s St. Paul’s Hospital, a University of British Columbia teaching hospital, the HLI is a translational research centre using basic molecular and cellular research discoveries to develop innovative approaches to prevent and treat human disease through complementary and connected clinical research.
The HLI focuses on developing solutions to diseases that are major causes of morbidity, mortality, and societal costs in Canada and worldwide. These include atherosclerosis and heart failure, emphysema and other chronic pulmonary diseases, severe infections, and multiple organ failure. The centre seeks out the underlying causes in order to develop strategies for prevention and treatment. Basic discoveries are linked to improved health care through clinical research and teaching, and by translating new knowledge into clinical practice at St. Paul’s Hospital and around the world.
HLI is one of several renowned research centres based at Providence Research.
Funding interests
Award type
Research Trainee, Scholar
Research interests
- pulmonary (respiratory, ventilation)
- cardiovascular (heart, vascular)
- ICU with a focus on sepsis (specifically bacterial clearance and/or the host response)
Research location/affiliation: Providence Health Care/Providence Research/Centre for Heart Lung Innovation
Awards
2022
Recipient
Yasir MohamudAward type
Research Trainee award
Project title
Innate immune mechanisms of viral myocarditis: Role of the cytosolic DNA-sensing pathway
Recipient
Stephanie SellersAward type
Scholar award
Project title
Valvular heart disease and bioprosthetic heart valves: Defining mechanisms of degeneration and therapeutic discovery from bedside to bench
2021
Recipient
Ana Hernandez CorderoAward type
Research Trainee award
Project title
Understanding the link between lung genomics, transcriptomics, and sex differences in COPD
2020
Recipient
Rachel EddyAward type
Research Trainee award
Project title
Ventilation Heterogeneity in Asthma, COPD and Asthma-COPD Overlap: Oscillometry and Pulmonary MRI
2019
Recipient
Michele SchaefferAward type
Research Trainee award
Project title
The effects of 60% oxygen during exercise training in patients with fibrotic interstitial lung disease
2018
Recipient
Yannick Molgat-SeonAward type
Research Trainee award
Project title
Investigating the role of skeletal muscle dysfunction on dyspnea and exercise intolerance in interstitial lung disease
Recipient
Stephanie SellersAward type
Research Trainee award
Project title
Structural valve degeneration in bioprosthetic heart valves