Raghu Sundaresan Nagalingam

Dr. Raghu Sundaresan Nagalingam is a postdoctoral research fellow in Dr. Glen Tibbits’s laboratory, Cellular and Regenerative Medicine Centre at BC Children’s Hospital Research Institute. He is affiliated with the Department of Biomedical Physiology and Kinesiology at Simon Fraser University.

Raghu holds a PhD in cardiac physiology and pathophysiology from the University of Manitoba, mentored by Dr. Michael P. Czubryt. During his doctoral thesis, he explored how scleraxis regulates cardiac fibrosis and contributes to heart failure. This study revealed a critical scleraxis-dependent mechanism in pressure overload-induced cardiac fibrosis.

His doctoral research was supported by Research Manitoba. His current research focuses on stress-mediated pathological signaling and cell-to-cell communication in clinically relevant hypertrophic cardiomyopathy, and atrial fibrillation mutant cardiomyocytes (CMs) and fibroblasts (FBs) derived from hiPSCs. This study will help understand the profibrotic signaling in CMs and FBs, leading to targeted anti-fibrotic drug development.

For an up-to-date list of Raghu’s publications, see Google Scholar.