Keegan (she/her/hers) is an assistant professor in the Department of Statistics at the University of British Columbia and an investigator in the Centre for Molecular Medicine and Therapeutics at the BC Children’s Hospital Research Institute. Her research group tackles the challenging task of uncovering meaningful biological insights from large-scale genomic experiments. Innovative technologies now allow scientists to probe the genome in more dimensions and at higher resolution than ever before, providing a wealth of information for studying the genomic basis of complex traits. However, discoveries from these new technologies can often be masked by technical artifacts, systematic biases, or low signal-to-noise ratio – think “needle in a haystack”. Keegan leads a team of researchers that focuses on developing rigorous statistical frameworks and computational tools that exploit the increased scope and scale of high-throughput sequencing data, with the ultimate goal of uncovering new molecular signals in cancer, child health, and development.