Andrew Sandford

Dr. Andrew Sandford is an associate professor in the Respiratory Division of the Faculty of Medicine at the University of British Columbia. He is partly funded by a Michael Smith Foundation for Health Research Senior Scholar Award.

His research program is focused on the genetic susceptibility to inflammatory lung diseases, including genetic risk factors for the development of asthma and chronic obstructive pulmonary disease as well as genetic modifiers of disease severity in cystic fibrosis. He is also investigating the functional impact of genetic variants that have been associated with respiratory disease.

Recent Publications

Madore AM, Vaillancourt VT, Asai Y, Alizadehfar R, Ben-Shoshan M, Michel DL, Kozyrskyj AL, Becker A, Chan-Yeung M, Clarke AE, Hull P, Daley D, Sandford AJ, Laprise C. HLA-DQB1*02 and DQB1*06:03P are associated with peanut allergy. Eur J Hum Genet. 2013 Feb 27. doi: 10.1038/ejhg.2013.13. (PubMed abstract)

Daley D, Park JE, He JQ, Yan J, Akhabir L, Stefanowicz D, Becker AB, Chan-Yeung M, Bossé Y, Kozyrskyj AL, James AL, Musk AW, Laprise C, Hegele RG, Paré PD, Sandford AJ. Associations and interactions of genetic polymorphisms in innate immunity genes with early viral infections and susceptibility to asthma and asthma-related phenotypes. J Allergy Clin Immunol. 2012 Dec;130(6):1284-93. doi: 10.1016/j.jaci.2012.07.051. Epub 2012 Oct 9. (PubMed abstract)

Sandford AJ, Malhotra D, Boezen HM, Siedlinski M, Postma DS, Wong V, Akhabir L, He JQ, Connett JE, Anthonisen NR, Paré PD, Biswal S. NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease. Physiol Genomics. 2012 Aug 1;44(15):754-63. doi: 10.1152/physiolgenomics.00027.2012. Epub 2012 Jun 12. (PubMed abstract)

Aminuddin F, Akhabir L, Stefanowicz D, Paré PD, Connett JE, Anthonisen NR, Fahy JV, Seibold MA, Burchard EG, Eng C, Gulsvik A, Bakke P, Cho MH, Litonjua A, Lomas DA, Anderson WH, Beaty TH, Crapo JD, Silverman EK, Sandford AJ. Genetic association between human chitinases and lung function in COPD. Hum Genet. 2012 Jul;131(7):1105-14. doi: 10.1007/s00439-011-1127-1. Epub 2011 Dec 28. (PubMed abstract)

Park JE, Yung R, Stefanowicz D, Shumansky K, Akhabir L, Durie PR, Corey M, Zielenski J, Dorfman R, Daley D, Sandford AJ. Cystic fibrosis modifier genes related to Pseudomonas aeruginosa infection. Genes Immun. 2011 Jul;12(5):370-7. doi: 10.1038/gene.2011.5. Epub 2011 Jan 27. (PubMed abstract)