Risk Reduction in Mental Health

Individuals with a major mental disorder are at heightened risk of committing acts of violence, being victimized by others, and harming themselves. These adverse outcomes – and the factors that contribute or mitigate them – are known to be interconnected. However, there hasn’t been a coordinated research platform that addresses all three outcomes together and identifies how different risk and protective factors affect each of these outcomes individually, and in combination, over time.

This team will link together researchers across BC and around the world to identify the most important dynamic risk and protective factors for violence, and determine the best techniques to measure and analyze their change over time. Because many individuals with a major mental disorder also have problems related to substance use, the team will also assess the relationship between mental health, substance use and violence.

COPD And Inflammation Team (CAIT)

In BC, more than 74,000 adults have chronic obstructive pulmonary disease (COPD) and 10,000 patients require hospitalization each year for related illnesses, such as chronic bronchitis and emphysema. Lung inflammation is the defining symptom of COPD, and may also be responsible for its progression and complications, including lung cancer and vascular disease. Currently, there are few effective therapies available to treat COPD. This unit’s research will bring together basic scientists, clinicians and epidemiologists to focus on identifying and understanding the complex inflammatory cascades of COPD. The team’s ultimate goal is to find new strategies and therapies to improve health outcomes of patients with COPD.

BC Team to Study the Origins of Asthma and Allergy

This award funds the creation of a research team focused on studying the genetic, immune and environmental factors that lead to allergic diseases and asthma. The team’s goals will be to identify factors and pathways that influence development of allergies; assess the environmental agents relevant to asthma and allergies; support the development of allergic diseases personnel; partner with national and international researchers to secure sustainable research support; and advance knowledge of allergic diseases.

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Interdisciplinary Team Generating Research on Complex Patients to Develop Innovative Solutions

This award funds the creation of a transdisciplinary team studying health issues of complex patient groups with multiple illnesses, and varied ethnicities and socio-economic backgrounds. The goal is to examine the health status and trajectory of these patients by integrating research about the social determinants that affect their health, such as education, housing status, and income level.

Developmental Neuroscience Research Team for Behavioural Self Regulation

This award supports the development of a team of clinicians and researchers addressing gaps of understanding about the causes of developmental disorders including Fetal Alcohol Spectrum Disorder, Attention Deficit Hyperactive Disorder and Conduct Disorder. These gaps include the electrophysiological processes underlying problems in social development, such as self-regulation, that affect children diagnosed with these disorders.

The British Columbia Fatigue Research Group

This award funds the creation of a research team focused on understanding fatigue associated with neurologic and neuromuscular disorders. The goal is to develop an interdisciplinary approach to research, exploring the prevalence of fatigue among individuals with disabilities, how and to what extent the condition influences function and quality of life, what are the costs to society and the health system and, ultimately, how to improve treatment.

PREDICT: Personalized Response Determinants in Cancer Therapy

This award supports the development of an interdisciplinary team that embeds research into front line cancer care. The goal is to develop a blood and DNA bank from consenting patients with newly diagnosed cancer, to serve as a resource for studying the causes of cancer as well as responses to, and outcome of, cancer therapies.

Collaborative Research Team for the Study of Bipolar Disorder (CREST.BD)

This award funds the development of a multidisciplinary research team focused on examining and developing a knowledge base on the role of psychosocial factors in bipolar disorder. The goals include: identifying research priorities within the field of psychosocial issues in bipolar disorder; ensuring the team has the skills and expertise to address these priorities; identifying and establishing partnerships with existing organizations; developing research plans and a patient-centered research agenda; and identifying opportunities for sharing and leveraging resources.