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…function, this research will also contribute new knowledge about healthy brain development. Leader: Michael Hayden, MB, PhD, FRCPC University of British Columbia Members: Alaa El-Din El-Husseini, PhD University of British…
…components of tumours were originally connected. As a final step in his research, he will investigate the key protein modification patterns (or “”””signatures””””) found in the mouse model and see…
…experiments leading to two valuable outcomes. First, the discovery of new genes that regulate GCase could provide new targets for potential treatments. Second, we expect these findings will uncover new…
…existing neurons. These processes all occur within the extracellular matrix (ECM) – a network of fibrous proteins, gel-like sugars and linking molecules – and are promoted by a large number…
…all genetics research, it is difficult to produce. Methods to rewrite or create new DNA sequences from scratch are limited. Regions of DNA can be copied, but there are relatively…
…mobility challenges (e.g. women, new immigrants, older adults). The work will focus on how an investment in a city-wide cycling network for people of all ages and abilities impacts uptake,…
…of new drugs for the treatment of cancer, diabetes, infectious diseases and other acute and chronic health problems. This drug development and commercialization platform provides a structure and process for…
…of British Columbia Members: Jan Dutz, MD, FRCPC University of British Columbia Diane Finegood, PhD Simon Fraser University Rusang Tan, MD, FRCPC, PhD University of British Columbia Jean-Pierre Chanoine, MD,…
…distinct characteristics. Marrying this information to new biomarkers may help determine whether any new biomarker is associated with positive (i.e. cure), or negative (i.e. relapse), clinical outcomes. Finally, the identification…
…the first detailed molecular structural analysis of these important drug resistance signaling proteins. Obtaining the necessary quantity of materials for structural investigation has proven notoriously challenging, so a “”cell-free”” protein…