…cells in a part of the brain called the substantia nigra. There is no definitive test to diagnose Parkinson’s disease, making it difficult to diagnose in its early stages. By…
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…to the health care system without inducing resistant superbugs. Project Objective: To develop and test a novel peptide (protein) coating on urinary devices to reduce device-related urinary tract infection. Work…
…human enzymes will offer a more economical way to provide ERT treatments for MPS I, as well as for Gaucher disease, another lysosomal storage disease. She will test whether plant-made…
…chemotherapy treatment – information that is not currently available. Specifically, she will frequently test indicators of physical fitness in a group of breast cancer patients who are participating in an…
…test that will allow for better identification of risk factors and improved treatment and monitoring that will increase the safety of anthracycline therapy. Study participants have been recruited via the…
…adults with prediabetes. Dr. Jung’s program of research aims to develop and test novel, feasible, and translatable self-regulatory training techniques. Her hypothesis is that brief SCT interventions provide a practical…
…HIV and Hepatitis C outcomes and engagement in associated care; mental illness; and self-reported health. Second, Dr. Richardson will conduct social and structural intervention studies that test innovative strategies to…
…(RPTPs). To test this, we will use a combination of cell cultures and mouse models. We will test whether APP binds to neurexins and RPTPs and whether binding to these…
…the production of reactive oxygen species (ROS)-a group of harmful chemical agents that can directly activate pannexins. For the present proposal, we will test the hypothesis that pannexin activation is…
…The team also plans to develop a mouse model of frontotemporal dementia to test the small molecule combinations in a living organism. The long-term goal of the project is…