Zhizeng Gao

Recent Publications

Gao Z, Wang J, Norquay AK, Qiao K, Tang Y, Vederas JC. Investigation of fungal iterative polyketide synthase functions using partially assembled intermediates. J Am Chem Soc. 2013 Feb 6;135(5):1735-8. doi: 10.1021/ja4001823. Epub 2013 Jan 28. (PubMed abstract)

Pyle BW, Tran HT, Pickel B, Haslam TM, Gao Z, MacNevin G, Vederas JC, Kim SU, Ro DK. Enzymatic synthesis of valerena-4,7(11)-diene by a unique sesquiterpene synthase from the valerian plant (Valeriana officinalis). FEBS J. 2012 Sep;279(17):3136-46. doi: 10.1111/j.1742-4658.2012.08692.x. Epub 2012 Jul 25. (PubMed abstract)

Zhou H, Gao Z, Qiao K, Wang J, Vederas JC, Tang Y. A fungal ketoreductase domain that displays substrate-dependent stereospecificity. Nat Chem Biol. 2012 Mar 11;8(4):331-3. doi: 10.1038/nchembio.912. (PubMed abstract)

Zhou H, Qiao K, Gao Z, Vederas JC, Tang Y. Insights into radicicol biosynthesis via heterologous synthesis of intermediates and analogs. J Biol Chem. 2010 Dec 31;285(53):41412-21. doi: 10.1074/jbc.M110.183574. Epub 2010 Oct 20. (PubMed abstract)

Zhou H, Qiao K, Gao Z, Meehan MJ, Li JW, Zhao X, Dorrestein PC, Vederas JC, Tang Y. Enzymatic synthesis of resorcylic acid lactones by cooperation of fungal iterative polyketide synthases involved in hypothemycin biosynthesis. J Am Chem Soc. 2010 Apr 7;132(13):4530-1. doi: 10.1021/ja100060k. (PubMed abstract)