Immune cells are critical for fighting off infections and repairing damaged tissues but chronic over-activation of immune cells can contribute to the development of various diseases that plague modern society.
My research focuses on molecules known as “anti-inflammatory cytokines” that prevent over-activation of immune cells. I am particularly interested in how Type 2 diabetes impacts the ability of interleukin-10 (a key anti-inflammatory cytokine) to prevent immune cell over-activation and strategies to restore defects in interleukin-10 function in people with diabetes.
My hope is that a better understanding of how interleukin-10 function is impacted by Type 2 diabetes will contribute to the development of lifestyle and pharmaceutical interventions aimed at restoring anti-inflammatory cytokine action for the prevention and treatment of Type 2 diabetes.
For an up-to-date list of publications by Hashim, please see ResearchGate.
His publications are also available on Google Scholar.