Population-Based Analysis of Nontuberculous Mycobacterial Pulmonary Disease in British Columbia

Nontuberculous mycobacteria (NTM) are a group of environmental bacteria, commonly found in the water and soil. Many species of NTM – such as Mycobacterium avium complex – can cause chronic lung infections, which are difficult to treat and often associated with progressive lung damage. The number of people affected by NTM lung disease has been increasing around the world, however, we do not have a good understanding of its local impact. In this project, we will use province-wide data to characterize the scope of NTM lung disease in British Columbia (BC) and examine treatment patterns. We will also assess challenges associated with treatment, including early treatment discontinuation and bacterial resistance to antibiotics. Findings from this study will improve our understanding of the patient population affected by NTM lung disease in BC and inform efforts to improve the care of these patients.